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Molecular Mycology
Molecular Mycology: Current Approaches to Fungal Pathogenesis

Course Directors: J. Andrew Alspaugh, Duke University Medical Center, and Deborah A. Hogan, Dartmouth Medical School

Course Date: July 31 - August 16, 2013
Online Application Form, Deadline: April 10, 2013

2012 Schedule (PDF)

This course is designed to train advanced graduate students, post-docs, and independent investigators in different molecular methods used to study human fungal pathogens, and the models at the forefront of research to uncover the mechanisms that underlie fungal diseases and their treatment. Limited to 18 students.

Training is provided through laboratory exercises and demonstrations, lectures by resident faculty and visiting seminar speakers, and informal panel discussions. Laboratory exercises focus primarily on Candida, Aspergillus, and Cryptococcus, and focus on different areas such as genetic manipulation of fungi, cell culture and in vivo pathogenicity and host response assays, genomic analyses, assessment of genome instability, antifungal resistance assays, and the microscopic analysis of fungi. Students are presented with the current views of pathogenesis of different key human fungal pathogens and the approaches used to study these fungi. In order to broaden students understanding of the field, invited seminar speakers provide further insight into Candida, Aspergillus, Cryptococcus biology and present work on other fungi such as Histoplasma, Coccidioides, and Pneumocystis. Specialized lectures in areas relating to drug discovery, molecular diagnostic techniques, virulence, genome structure and evolution, mating, vaccine strategies, and host defenses are also included. Panel discussions focus on issues in medical mycology, development of new research techniques and paradigms, and topics relating to professional development within the field of fungal pathogenesis.


This course is supported with funds provided by
Burroughs Wellcome Fund
Howard Hughes Medical Institute

2013 Faculty and Lecturers:

Richard Bennett, Brown University
Alistair Brown, University of Aberdeen
Arturo Casadevall, Albert Einstein College of Medicine
Robert Cramer, Dartmouth Medical School
George Deepe, University of Cincinnati School of Medicine
Jack Edwards, Harbor-UCLA Medical Center
Amy Gladfelter, Dartmouth University
Joseph Heitman, Duke University School of Medicine
James Konopka, Stony Brook University
James Kronstad, University of British Columbia
Damian Krysan, University of Rochester School of Medicine
Xiaorong Lin, Texas A and M University
Aaron Mitchell, Carnegie-Mellon University
Lefteris Mylonakis, Brown University School of Medicine
Suzanne Noble, University of California-San Francisco School of Medicine
John Perfect, Duke University School of Medicine
Donald Sheppard, McGill University
Robert Wheeler, University of Maine
Ted White, University of Missouri – Kansas City

 
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