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The Cellular Dynamics Program (CDP) at the MBL aims to accelerate the knowledge of basic biology and disease through the development and utilization of tools customized to shed light on lifes most essential processes. It merges the extraordinary imaging talents of the Architectural Dynamics in Living Cells (ADLC) program with the unique expertise of the Molecular Physiology Program (MPP) and the BioCurrents Research Center (BRC).
CDP was established in 2008 and is composed of several independent laboratories, notably those with a specialization in imaging (Inoue, Oldenbourg and Shribak) and cell physiology and biochemistry (Gomez, Heart, Messerli, Nasi and Smith). Additionally the program houses the NIH:NCRR national resource, the BioCurrents Research Center. The CDP imaging component focuses on the architectural dynamics of living cells, which encompass the timely and coordinated assembly and disassembly of macromolecular structures essential for the proper functioning and differentiation of cells, the spatial and temporal organization of these structures, and their physiological and genetic control. The physiologically focused research, in addition to pursuing studies of biomedical relevance, cell metabolism and transport biophysics, has pioneered the use of electrochemical sensors to define the chemical signatures surrounding living cells and tissue, opening insights to cell function from a distance.
The CDP goals are to deepen existing research into critical cellular processes, such as cell motility, protein-protein interactions, molecular trafficking, molecular transport and metabolism, as well as signaling within and between cells. The Program provides crucial new windows on cells and cell division, while advancing key discoveries at the cellular level by supporting the development of groundbreaking new instrumentation and techniques for studying and manipulating living cells. As a program goal, we aim to organize a group of like-minded collaborative and teaching scientists, sharing an interest in molecular process, cellular plasticity and biophysics. The Program aims to provide a resident focus to the overall MBL activities in cell biology research and education.
Faculty:
Program Director: Peter J.S. Smith
Gary Borisy
Maria Gomez
Emma Heart
Shinya Inoué
Mark Messerli
Shanta Messerli
Enrico Nasi
Rudolf Oldenbourg
Harris Ripps
Michael Shribak
Administrative Coordinators:
Jane MacNeil (S. Inoue)
Tiffany Van Mooy (P.J.S. Smith) |
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Research:
Tamara Clark
Leon Collis
David Graham
Grant Harris
Robert Lewis
Anoop Menachery (Graduate Student)
Richard Sanger
Alex Valm (Graduate Student)
Lina Moitoso de Vargas
Adjunct Faculty:
Jella Atema, Boston University
David Burgess, Boston College
Miguel Holmgren, NINDS
George Holz, SUNY
Lin Liu, University of Southern Florida
Ron Pethig, University of Wales |
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