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Laboratory of Shinya Inoué

Administrative Staff: Jane MacNeil - jmacneil@mbl.edu

Phone (508) 289-7382
Fax (508) 540-6902
E-Mail jmacneil@mbl.edu

Marine Biological Laboratory
7 MBL Street
Woods Hole, MA 02543
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Research Interests:
Shinya Inoué’s laboratory pursues studies of the molecular mechanism and control of mitosis, cell division, and cell morphogenesis, with emphasis on biophysical studies made directly on single living cells, especially developing eggs in marine invertebrates. Development of biophysical instrumentation and methodology, such as the centrifuge polarizing microscope, high-extinction polarization optical and video microscopy, digital image processing techniques including dynamic stereoscopic imaging, and exploration of their underlying theory are an integral part of the laboratory's effort.

Distinguished Scientist Shinya Inoué, Cellular Dynamics Program

Shinya Inoue Education:

1951    Ph.D. Biology, Princeton University
1950    M.A. Biology, Princeton University
1944    Rigakushi Zoology, Tokyo University

  • Government of Japan, Order of the Sacred Treasure, Gold Rays with Neck Ribbon Award, June 10, 2010
  • International Prize for Biology from the Japan Society for the Promotion of Science, December 2003
  • National Academy of Sciences, Elected, April 1993

Selected Publications:

2009 Goda, M., S. Inoué, and I. Mabuchi. Calyculin-A induces cleavage in a
random plane in unfertilized sea urchin eggs. Biol. Bull. 216: 40-44.

2008 Shribak, M., J. LaFountain, D. Biggs, and S. Inoué, Orientation-independent differential interference contrast microscopy and its combination with an orientation-independent polarization system. Journal of Biomedical Optics 13(1): 014011.

2008 Inoué, S. Collected Works of Shinya Inoué: Microscopes, Living Cells, and Dynamics Molecules. World Scientific Publishing Co., Singapore.

2008 Inoué, S. Microtubule Dynamics in Cell Division: Exploring Living Cells with Polarized Light Microscopy. Annu. Rev. Cell Dev. Biol. 24:1-28, 2008.

2007 Shribak, M., J. LaFountain, D. Biggs, and S. Inoué. Quantitative orientation-independent differential interference contrast (DIC) microscopy coupled with orientation-independent polarization microscopy. In C. Lyman et al., eds., Proceedings of Microscopy and Microanalysis 2007. Cambridge University Press, pp. 10-12.

2007 Shribak, M., J. LaFountain, D. Biggs, and S. Inoué. Quantitative orientation-independent differential interference contrast (DIC) microscopy. In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V, D.L. Farkas et al, Editors, Proc. SPIE 6441, p. 64411L1-6441L12.

2006 Shribak, M., and S. Inoué. Orientation-independent differential interference contrast microscopy. Applied Optics 45(3): 460-469.

2006 Hoffman, J.F., and S. Inoué. Directly observed reversible shape changes and hemoglobin stratification during centrifugation of human and Amphiuma red blood cells. Proc. Natl. Acad. Sci. USA 103(8): 2971-2976.

2006 Inoué, S. In memory of Hidemi Sato. Biol. Cell. 98(10): e1-e2.

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